Medical Research


The Specific Carbohydrate diet is outlined in the book Breaking the Vicious Cycle by Elaine Gottschall. It is important to read the book to understand the science behind the diet and to implement it correctly. The following excerpts are from peer reviewed medical research about the SCD.

1-      The Specific Carbohydrate Diet for Inflammatory Bowel Disease: A Case Series.  2015 Journal of the Academy of Nutrition and Dietetics https://jandonline.org/article/S2212-2672(15)00504-3/fulltext

This gives a good overview of the SCD.

 Conclusion:
“This is the first clinical description of a large series of patients with IBD following the SCD. Our survey results suggest that SCD can potentially be an effective tool in the management of some patients with IBD and specifically in patients with colonic and ileocolonic CD who made up the majority of our study group. A highly educated group of patients follow the SCD; all but one of the adults in our study had a college or graduate degree. Our results also suggest that in some patients with moderate to severe disease who follow this diet, discontinuation of immunosuppressive agents has been feasible.”


2-     Clinical and Fecal Microbial Changes with Diet Therapy in Active Inflammatory Bowel Disease. 2018 Journal of clinical gastroenterology https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484760/

Conclusion:
“SCD therapy in IBD is associated with clinical and laboratory improvements as well as concomitant changes in the fecal microbiome. Further prospective studies are required to fully assess the safety and efficacy of dietary therapy in patients with IBD.”


3-      Nutritional Adequacy of the Specific Carbohydrate Diet in Pediatric Inflammatory Bowel Disease. 2017 Journal of pediatric gastroenterology and nutrition. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653423

“Energy intake was significantly greater than 100% of the Recommended Daily Allowance (RDA)/Adequate Intake (AI) for 64% of daily intakes completed for this study. The majority of participants' daily intakes met or exceeded the RDA for vitamins B2, B3, B5, B6, B7, B12, C, A, and E. One hundred percent of participants' intakes were below the RDA for vitamin D. Seventy-five percent of daily intakes were less than the RDA for calcium. The upper limit was met or exceeded for magnesium in 42% of daily intakes. Average Vitamin A intake was significantly greater than the upper limit (p=0.01).”


4-      The Specific Carbohydrate Diet in the Treatment of Crohn’s Disease: A Systematic Review 2017 Journal of Gastroenterology and Hepatology Research http://ghrnet.org/index.php/joghr/article/view/1957/2437

This article gives a review of the current research of the Specific Carbohydrate Diet with Crohn’s disease.

 “Overall, each included study reported findings that indicate clinical benefits of the SCD in the management of CD.”
Conclusion: “As previously stated, there is increasing interest in the use of oral diet therapy in the treatment of CD. As this review demonstrated, the SCD has been associated with significant clinical improvements for many patients, including achievement and maintenance of remission from active disease. The SCD may indeed prove to be a viable, safe, and effective treatment for CD. However, it must be emphasized that stronger study designs are needed to better investigate the true efficacy of the SCD.”


5-      A Review of Dietary Therapy for IBD and a Vision for the Future 2019 Nutrients

This article focuses on dietary therapy in general, it is not SCD specific. It looks at the role of the modern diet and microbiome in IBD and the future of dietary therapies.

“Current IBD therapy focuses on suppression of the immune system, yet the incomplete efficacy of present drugs suggests that other therapies must be developed and employed. Dietary interventions, with known ability to modulate the intestinal microbiome, are a unique opportunity to improve outcomes in IBD.”

“many diets have been reported to be efficacious in small case series, including the specific carbohydrate diet (SCD), IBD anti-inflammatory diet (IBD-AID), Crohn’s disease exclusion diet (CDED), and semi-vegetarian diet [13]. The SCD developed by Dr. Sydney Haas, a pediatrician, in the 1930s to treat patients with celiac disease has been one of the better studies of exclusion diets used in IBD”

“diet is a potential target for profound intervention. Dietary intervention with EEN or even a shift in fat and fiber consumption results in a tangible shift in the intestinal microbiome.”


There are links to many more peer reviewed medical journal articles available at: http://www.scdrecipe.com/medical-journal-articles/list